Canadian COVID-19 Emergency Department Rapid Response Network

Project Description

The Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN, pronounced SE-DRIN) is a national collaboration with Public Health partners to harmonize data collection related to COVID-19 in fifty Emergency Departments (EDs) across 8 provinces (BC, AB, SK, MB, ON, QC, NS, NB). When the pandemic struck, Emergency physicians lacked high-quality evidence for many diagnostic and treatment decisions made for patients with suspected or confirmed coronavirus disease 2019 (COVID-19). With the financial support of the Canadian Institutes of Health Research (CIHR), the COVID-19 Immunity Task Force (CITF) and Public Health Agency of Canada (PHAC), CCEDRRN generated a high-quality clinical dataset on patients who presented to EDs and were tested for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2).

Most data were collected from retrospective chart review. Phone follow-ups with patients captured the contextual, social and cultural variables, vaccine status and patient-reported quality of life. In June of 2021, on behalf of CCEDRRN, Dr Archambault was granted additional funding from CIHR to investigate the Post-COVID-19 Condition (PCC). The phone follow-up questionnaire was adapted to assess PCC issues in ED patients.

Overall, the fifty participating emergency departments enrolled over 208,000 patients into the registry. In addition, data on 12,000 participants have been collected to better understand the Post-COVID-19 Condition. To date, 21 manuscripts have been published by CCEDRRN investigators and 15 more are in progress.

Trial registration: Clinicaltrials.gov, no. NCT04702945
Project full title: Learning in a Time of Crisis: Creating a Canadian Emergency Department COVID-19 Registry (Quebec)

Archambault team publications associated with this project:

Post-COVID-19 condition symptoms among emergency department patients tested for SARS-CoV-2 infection

Accuracy of Self-Reported COVID-19 Vaccination Status Compared With a Public Health Vaccination Registry in Québec: Observational Diagnostic Study

Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study

CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19

Derivation and Validation of a Clinical Score to Predict Death among Non-Palliative COVID-19 Patients Presenting to Emergency Departments: The CCEDRRN COVID Mortality Score

Reducing barriers to accessing administrative data on SARS-CoV-2 vaccination for research

Patient-reported health outcomes of SARS-COV-2 tested patients presenting to emergency departments: a propensity-score matched prospective cohort study

ALL Publications by CCEDRRN